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Hexavalent Chromium (Cr(VI)) Down-Regulates Acetylation of Histone H4 at Lysine 16 through Induction of Stressor Protein Nupr1

The environmental and occupational carcinogen Hexavalent Chromium (Cr(VI)) has been shown to cause lung cancer in humans when inhaled. In spite of a considerable research effort, the mechanisms of Cr(VI)-induced carcinogenesis remain largely unknown. Nupr1 (nuclear protein 1) is a small, highly basi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chen, Danqi, Kluz, Thomas, Fang, Lei, Zhang, Xiaoru, Sun, Hong, Jin, Chunyuan, Costa, Max
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902237/
https://ncbi.nlm.nih.gov/pubmed/27285315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157317
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