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Ultrasonic stimulation of mouse skin reverses the healing delays in diabetes and aging by activation of Rac1

Chronic skin healing defects are one of the leading challenges to lifelong wellbeing, affecting 2-5% of populations. Chronic wound formation is linked to age and diabetes and frequently leads to major limb amputation. Here we identify a strategy to reverse fibroblast senescence and improve healing r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Invest Dermatol
Hauptverfasser: Roper, James A, Williamson, Rosalind C, Bally, Blandine, Cowell, Christopher AM, Brooks, Rebecca, Stephens, Phil, Harrison, Andrew J, Bass, Mark D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902130/
https://ncbi.nlm.nih.gov/pubmed/26079528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.224
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