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Proliferation Of Double Strand Break Resistant Polyploid Cells Requires Drosophila FANCD2
Conserved DNA damage responses (DDRs) sense genome damage and prevent mitosis of broken chromosomes. How cells lacking DDRs cope with broken chromosomes during mitosis is poorly understood. DDRs are frequently inactivated in cells with extra genomes (polyploidy), suggesting study of polyploidy can r...
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| Publicado no: | Dev Cell |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4901310/ https://ncbi.nlm.nih.gov/pubmed/27270041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.05.004 |
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