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Proliferation Of Double Strand Break Resistant Polyploid Cells Requires Drosophila FANCD2
Conserved DNA damage responses (DDRs) sense genome damage and prevent mitosis of broken chromosomes. How cells lacking DDRs cope with broken chromosomes during mitosis is poorly understood. DDRs are frequently inactivated in cells with extra genomes (polyploidy), suggesting study of polyploidy can r...
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| Udgivet i: | Dev Cell |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4901310/ https://ncbi.nlm.nih.gov/pubmed/27270041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.05.004 |
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