Oxidative Stress Mediates the Antiproliferative Effects of Nelfinavir in Breast Cancer Cells

The discovery of the anti-proliferative activity of nelfinavir in HIV-free models has encouraged its investigation as anticancer drug. Although the molecular mechanism by which nelfinavir exerts antitumor activity is still unknown, its effects have been related to Akt inhibition. Here we tested the...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Soprano, Maria, Sorriento, Daniela, Rusciano, Maria Rosaria, Maione, Angela Serena, Limite, Gennaro, Forestieri, Pietro, D’Angelo, Dario, D’Alessio, Matteo, Campiglia, Pietro, Formisano, Pietro, Iaccarino, Guido, Bianco, Roberto, Illario, Maddalena
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900679/
https://ncbi.nlm.nih.gov/pubmed/27280849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155970
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