Evaluation of cytochrome P450 2C9 activity in normal, healthy, adult Western Indian population by both phenotyping and genotyping

OBJECTIVES: Cytochrome P450 2C9 (CYP2C9) is a member of cytochrome P450 (CYP) family that accounts for nearly 18% of the total CYP protein content in the human liver microsomes and catalyzes almost 15–20% of the drugs. Considering the paucity of data on the polymorphisms of CYP2C9 in Western Indian...

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Publicat a:Indian J Pharmacol
Autors principals: Swar, Balkrishna D., Bendkhale, Shital R., Rupawala, Abbas, Sridharan, Kannan, Gogtay, Nithya J., Thatte, Urmila M., Kshirsagar, Nilima A.
Format: Artigo
Idioma:Inglês
Publicat: Medknow Publications & Media Pvt Ltd 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899995/
https://ncbi.nlm.nih.gov/pubmed/27298492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0253-7613.182885
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