A replicator-specific binding protein essential for site-specific initiation of DNA replication in mammalian cells

Mammalian chromosome replication starts from distinct sites; however, the principles governing initiation site selection are unclear because proteins essential for DNA replication do not exhibit sequence-specific DNA binding. Here we identify a replication-initiation determinant (RepID) protein that...

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Publicat a:Nat Commun
Autors principals: Zhang, Ya, Huang, Liang, Fu, Haiqing, Smith, Owen K., Lin, Chii Mei, Utani, Koichi, Rao, Mishal, Reinhold, William C., Redon, Christophe E., Ryan, Michael, Kim, RyangGuk, You, Yang, Hanna, Harlington, Boisclair, Yves, Long, Qiaoming, Aladjem, Mirit I.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899857/
https://ncbi.nlm.nih.gov/pubmed/27272143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11748
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