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Elevation of serum sphingosine-1-phosphate attenuates impaired cardiac function in experimental sepsis
Serum levels of the lipid mediator sphingosine-1-phosphate (S1P) are reduced in septic patients and are inversely associated with disease severity. We show that serum S1P is reduced in human sepsis and in murine models of sepsis. We then investigated whether pharmacological or genetic approaches tha...
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| Vydáno v: | Sci Rep |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4899780/ https://ncbi.nlm.nih.gov/pubmed/27277195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27594 |
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