Oestrogen and parathyroid hormone alleviate lumbar intervertebral disc degeneration in ovariectomized rats and enhance Wnt/β-catenin pathway activity

To investigate the mitigation effect and mechanism of oestrogen and PTH on disc degeneration in rats after ovariectomy, as well as on Wnt/β-catenin pathway activity, thirty 3-month-old rats were ovariectomized and divided into three groups. Ten additional rats were used as controls. Eight weeks late...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jia, Haobo, Ma, Jianxiong, Lv, Jianwei, Ma, Xinlong, Xu, Weiguo, Yang, Yang, Tian, Aixian, Wang, Ying, Sun, Lei, Xu, Liyan, Fu, Lin, Zhao, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899752/
https://ncbi.nlm.nih.gov/pubmed/27279629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27521
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