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Codon optimization of the adenoviral fiber negatively impacts structural protein expression and viral fitness
Codon usage adaptation of lytic viruses to their hosts is determinant for viral fitness. In this work, we analyzed the codon usage of adenoviral proteins by principal component analysis and assessed their codon adaptation to the host. We observed a general clustering of adenoviral proteins according...
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| Gepubliceerd in: | Sci Rep |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4899721/ https://ncbi.nlm.nih.gov/pubmed/27278133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27546 |
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