載入...

Transgene codon usage drives viral fitness and therapeutic efficacy in oncolytic adenoviruses

Arming oncolytic adenoviruses with therapeutic transgenes is a well-established strategy for multimodal tumour attack. However, this strategy sometimes leads to unexpected attenuated viral replication and a loss of oncolytic effects, preventing these viruses from reaching the clinic. Previous work h...

全面介紹

Na minha lista:
書目詳細資料
發表在:NAR Cancer
Main Authors: Núñez-Manchón, Estela, Farrera-Sal, Martí, Otero-Mateo, Marc, Castellano, Giancarlo, Moreno, Rafael, Medel, David, Alemany, Ramon, Villanueva, Eneko, Fillat, Cristina
格式: Artigo
語言:Inglês
出版: Oxford University Press 2021
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8210037/
https://ncbi.nlm.nih.gov/pubmed/34316705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/narcan/zcab015
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!