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Codon optimization of the adenoviral fiber negatively impacts structural protein expression and viral fitness
Codon usage adaptation of lytic viruses to their hosts is determinant for viral fitness. In this work, we analyzed the codon usage of adenoviral proteins by principal component analysis and assessed their codon adaptation to the host. We observed a general clustering of adenoviral proteins according...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4899721/ https://ncbi.nlm.nih.gov/pubmed/27278133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27546 |
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