Effects of Interleukin-1 Blockade with Anakinra on Aerobic Exercise Capacity in Patients with Heart Failure and Preserved Ejection Fraction (from the D-HART Pilot Study)

Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome of exercise intolerance due to impaired myocardial relaxation and/or increased stiffness. Patient with HFpEF often show signs of chronic systemic inflammation and experimental studies show that interleukin-1 (IL-1), a key...

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Detalhes bibliográficos
Publicado no:Am J Cardiol
Main Authors: Van Tassell, Benjamin Wallace, Arena, Ross, Biondi-Zoccai, Giuseppe, Canada, Justin McNair, Oddi, Claudia, Abouzaki, Nayef Antar, Jahangiri, Arehzo, Falcao, Raquel Appa, Kontos, Michael Christopher, Shah, Keyur Bharat, Voelkel, Norbert Felix, Dinarello, Charles Anthony, Abbate, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899612/
https://ncbi.nlm.nih.gov/pubmed/24262762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjcard.2013.08.047
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