Perineuronal Nets Suppress Plasticity of Excitatory Synapses on CA2 Pyramidal Neurons

Long-term potentiation of excitatory synapses on pyramidal neurons in the stratum radiatum rarely occurs in hippocampal area CA2. Here, we present evidence that perineuronal nets (PNNs), a specialized extracellular matrix typically localized around inhibitory neurons, also surround mouse CA2 pyramid...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Carstens, Kelly E., Phillips, Mary L., Pozzo-Miller, Lucas, Weinberg, Richard J., Dudek, Serena M.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899529/
https://ncbi.nlm.nih.gov/pubmed/27277807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0245-16.2016
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