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Thiol--Disulfide Exchange Reactions in the Mammalian Extracellular Environment

Disulfide bonds represent versatile posttranslational modifications whose roles encompass the structure, catalysis, and regulation of protein function. Due to the oxidizing nature of the extracellular environment, disulfide bonds found in secreted proteins were once believed to be inert. This notion...

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Detalhes bibliográficos
Publicado no:Annu Rev Chem Biomol Eng
Main Authors: Yi, Michael C., Khosla, Chaitan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899241/
https://ncbi.nlm.nih.gov/pubmed/27023663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-chembioeng-080615-033553
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