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Thiol-disulfide exchange in human growth hormone

PURPOSE: Thiol-disulfide exchange was monitored in recombinant human growth hormone (hGH) and in model tryptic peptides derived from hGH to investigate the effects of higher-order structure on the reaction. METHODS: Different free thiol-containing peptides, varying in length and amino acid sequence,...

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Publicado en:Pharm Res
Main Authors: Chandrasekhar, Saradha, Moorthy, Balakrishnan S., Xie, Ruichao, Topp, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854756/
https://ncbi.nlm.nih.gov/pubmed/26887678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-016-1879-3
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