Active and inactive enhancers co-operate to exert localized and long-range control of gene regulation

V(D)J recombination relies on the presence of proximal enhancers that activate the antigen receptor (AgR) loci in a lineage and stage specific manner. Unexpectedly we find that both active and inactive AgR enhancers co-operate to disseminate their effects in a localized and long-range manner. Here w...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Proudhon, Charlotte, Snetkova, Valentina, Raviram, Ramya, Lobry, Camille, Badri, Sana, Jiang, Tingting, Hao, Bingtao, Trimarchi, Thomas, Kluger, Yuval, Aifantis, Iannis, Bonneau, Richard, Skok, Jane A
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899175/
https://ncbi.nlm.nih.gov/pubmed/27239026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.087
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