Dysregulation of RBFOX2 is an early event in cardiac pathogenesis of diabetes

Alternative splicing (AS) defects that adversely affect gene expression and function have been identified in diabetic hearts; however, the mechanisms responsible are largely unknown. Here we show that the RNA-binding protein RBFOX2 contributes to transcriptome changes under diabetic conditions. RBFO...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Nutter, Curtis A., Jaworski, Elizabeth A., Verma, Sunil K., Deshmukh, Vaibhav, Wang, Qiongling, Botvinnik, Olga B., Lozano, Mario J., Abass, Ismail J., Ijaz, Talha, Brasier, Allan R., Garg, Nisha J., Wehrens, Xander H.T., Yeo, Gene W., Kuyumcu-Martinez, Muge N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899142/
https://ncbi.nlm.nih.gov/pubmed/27239029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.002
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