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THE MECHANISMS OF MALLORY-DENK BODY FORMATION ARE SIMILAR TO THE FORMATION OF AGGRESOMES IN ALZHEIMER’S DISEASE AND OTHER NEURODEGENERATIVE DISORDERS

There is a possibility that the aggresomes that form in the brain in neurodegenerative diseases like Altzheimer’s disease (AD) and in the liver where aggresomes like Mallory-Denk Bodies (MDB) form, share mechanisms. MDBs can be prevented by feeding mice sadenosylmethionine (SAMe) or betaine. Possibl...

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Detalhes bibliográficos
Publicado no:Exp Mol Pathol
Main Authors: French, SW, Mendoza, AS, Peng, Y
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899135/
https://ncbi.nlm.nih.gov/pubmed/27068270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2016.03.010
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