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Defining single molecular forces required for Notch activation using nano yoyo

Notch signaling, involved in development and tissue homeostasis, is activated at the cell-cell interface through ligand-receptor interactions. Previous studies have implicated mechanical forces in the activation of Notch receptor upon binding to its ligand. Here we aimed to determine the single mole...

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Detalles Bibliográficos
Publicado en:Nano Lett
Main Authors: Chowdhury, Farhan, Li, Isaac T. S., Ngo, Thuy T. M., Leslie, Benjamin J., Kim, Byoung Choul, Sokoloski, Joshua E., Weiland, Elizabeth, Wang, Xuefeng, Chemla, Yann R., Lohman, Timothy M., Ha, Taekjip
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899123/
https://ncbi.nlm.nih.gov/pubmed/27167603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.6b01403
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