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60 YEARS OF POMC: From POMC and αMSH to PAM, molecular oxygen, copper and vitamin C
A critical role for peptide C-terminal amidation was apparent when the first bioactive peptides were identified. The conversion of POMC into ACTH and then into αMSH, an amidated peptide, provided a model system for identifying the amidating enzyme. Peptidylglycine α-amidating monooxygenase (PAM), th...
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| Publicado en: | J Mol Endocrinol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4899100/ https://ncbi.nlm.nih.gov/pubmed/26667899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JME-15-0266 |
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