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PAM and Copper – a Gene/Nutrient Interaction Critical to Nervous System Function
Peptidylgycine α-amidating monooxygenase (PAM), a highly conserved copper-dependent enzyme, is essential for the synthesis of all amidated neuropeptides. Biophysical studies revealed that the binding of copper to PAM affects its structure, and cell biological studies demonstrated that the endocytic...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3732055/ https://ncbi.nlm.nih.gov/pubmed/20648645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22404 |
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