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DNA methylation of LINE-1 and Alu repetitive elements in relation to sex hormones and pubertal timing in Mexican-American children

BACKGROUND: The molecular mechanisms linking environmental exposures to earlier pubertal development are not well characterized. Epigenetics may play an important role, but data on the relationship between epigenetic marks and puberty, particularly in humans, is limited. METHODS: We used pyrosequenc...

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Publicat a:Pediatr Res
Autors principals: Huen, Karen, Harley, Kim, Kogut, Katherine, Rauch, Stephen, Eskenazi, Brenda, Holland, Nina
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899098/
https://ncbi.nlm.nih.gov/pubmed/26882368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2016.31
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