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DNA methylation of LINE-1 and Alu repetitive elements in relation to sex hormones and pubertal timing in Mexican-American children

BACKGROUND: The molecular mechanisms linking environmental exposures to earlier pubertal development are not well characterized. Epigenetics may play an important role, but data on the relationship between epigenetic marks and puberty, particularly in humans, is limited. METHODS: We used pyrosequenc...

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Vydáno v:Pediatr Res
Hlavní autoři: Huen, Karen, Harley, Kim, Kogut, Katherine, Rauch, Stephen, Eskenazi, Brenda, Holland, Nina
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899098/
https://ncbi.nlm.nih.gov/pubmed/26882368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2016.31
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