Quercetin induces caspase-dependent extrinsic apoptosis through inhibition of signal transducer and activator of transcription 3 signaling in HER2-overexpressing BT-474 breast cancer cells

Flavonoids are assumed to exert beneficial effects in different types of cancers at high concentrations. Yet, their molecular mechanisms of action remain unknown. The present study aimed to examine the effect of quercetin on proliferation and apoptosis in HER2-expressing breast cancer cells. The ant...

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I publikationen:Oncol Rep
Huvudupphovsmän: SEO, HYE-SOOK, KU, JIN MO, CHOI, HAN-SEOK, CHOI, YOUN KYUNG, WOO, JONG-KYU, KIM, MINSOO, KIM, ILHWAN, NA, CHANG HYEOK, HUR, HANSOL, JANG, BO-HYOUNG, SHIN, YONG CHEOL, KO, SEONG-GYU
Materialtyp: Artigo
Språk:Inglês
Publicerad: D.A. Spandidos 2016
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899028/
https://ncbi.nlm.nih.gov/pubmed/27175602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2016.4786
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