Induction of caspase-dependent extrinsic apoptosis by apigenin through inhibition of signal transducer and activator of transcription 3 (STAT3) signalling in HER2-overexpressing BT-474 breast cancer cells

Phytoestrogen intake is known to be beneficial to decrease breast cancer incidence and progression. But its molecular mechanisms of action are still unknown. The present study aimed to examine the effect of apigenin on proliferation and apoptosis in HER2-expressing breast cancer cells. In our experi...

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Dettagli Bibliografici
Pubblicato in:Biosci Rep
Autori principali: Seo, Hye-Sook, Jo, Jae Kyung, Ku, Jin Mo, Choi, Han-Seok, Choi, Youn Kyung, Woo, Jong-Kyu, in Kim, Hyo, Kang, Soo-yeon, Lee, Kang min, Nam, Koong Won, Park, Namkyu, Jang, Bo-Hyoung, Shin, Yong Cheol, Ko, Seong-Gyu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2015
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Original Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4708008/
https://ncbi.nlm.nih.gov/pubmed/26500281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20150165
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