MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis

Osteoarthritis (OA) is the most prevalent degenerative joint disease with multifactorial etiology caused by risk factors such as ageing, obesity and trauma. Previously, it was reported that the inhibition of microRNA-34a (miR-34a) may reduce rat chondrocyte apoptosis induced by IL-1β, whereas the mo...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Int J Mol Med
Päätekijät: YAN, SHIJU, WANG, MENG, ZHAO, JIAN, ZHANG, HONGTAO, ZHOU, CHENGPEI, JIN, LEI, ZHANG, YINGLONG, QIU, XIUCHUN, MA, BAOAN, FAN, QINGYU
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: D.A. Spandidos 2016
Aiheet:
Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899008/
https://ncbi.nlm.nih.gov/pubmed/27247228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2016.2618
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