MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis

Osteoarthritis (OA) is the most prevalent degenerative joint disease with multifactorial etiology caused by risk factors such as ageing, obesity and trauma. Previously, it was reported that the inhibition of microRNA-34a (miR-34a) may reduce rat chondrocyte apoptosis induced by IL-1β, whereas the mo...

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Publicado no:Int J Mol Med
Main Authors: YAN, SHIJU, WANG, MENG, ZHAO, JIAN, ZHANG, HONGTAO, ZHOU, CHENGPEI, JIN, LEI, ZHANG, YINGLONG, QIU, XIUCHUN, MA, BAOAN, FAN, QINGYU
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899008/
https://ncbi.nlm.nih.gov/pubmed/27247228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2016.2618
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