Hypothermic machine perfusion increases A20 expression which protects renal cells against ischemia/reperfusion injury by suppressing inflammation, apoptosis and necroptosis

There is an urgent need to improve the quality of donor organs obtained after cardiac death. In the present study, we examined the potential mechanisms through which A20 protects renal cells against ischemia/reperfusion injury (IRI) following either hypothermic machine perfusion (HMP) or static cold...

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Vydáno v:Int J Mol Med
Hlavní autoři: YANG, ZIXUAN, ZHONG, ZIBIAO, LI, MINGXIA, XIONG, YAN, WANG, YANFENG, PENG, GUIZHU, YE, QIFA
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899006/
https://ncbi.nlm.nih.gov/pubmed/27177159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2016.2586
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