Sustained proliferation in cancer: mechanisms and novel therapeutic targets

Proliferation is an important part of cancer development and progression. This is manifest by altered expression and/or activity of cell cycle related proteins. Constitutive activation of many signal transduction pathways also stimulates cell growth. Early steps in tumor development are associated w...

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Publicado no:Semin Cancer Biol
Main Authors: Feitelson, Mark A., Arzumanyan, Alla, Kulathinal, Rob J., Blain, Stacy W., Holcombe, Randall F., Mahajna, Jamal, Marino, Maria, Martinez-Chantar, Maria L., Nawroth, Roman, Sanchez-Garcia, Isidro, Sharma, Dipali, Saxena, Neeraj K., Singh, Neetu, Vlachostergios, Panagiotis J., Guo, Shanchun, Honoki, Kanya, Fujii, Hiromasa, Georgakilas, Alexandros G., Amedei, Amedeo, Niccolai, Elena, Amin, Amr, Ashraf, S. Salman, Boosani, Chandra S., Guha, Gunjan, Ciriolo, Maria Rosa, Aquilano, Katia, Chen, Sophie, Mohammed, Sulma I., Azmi, Asfar S., Bhakta, Dipita, Halicka, Dorota, Nowsheen, Somaira
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898971/
https://ncbi.nlm.nih.gov/pubmed/25892662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2015.02.006
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