Therapeutic targeting of replicative immortality

One of the hallmarks of malignant cell populations is the ability to undergo continuous proliferation. This property allows clonal lineages to acquire sequential aberrations that can fuel increasingly autonomous growth, invasiveness, and therapeutic resistance. Innate cellular mechanisms have evolve...

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Detalhes bibliográficos
Publicado no:Semin Cancer Biol
Main Authors: Yaswen, Paul, MacKenzie, Karen L., Keith, W. Nicol, Hentosh, Patricia, Rodier, Francis, Zhu, Jiyue, Firestone, Gary L., Matheu, Ander, Carnero, Amancio, Bilsland, Alan, Sundin, Tabetha, Honoki, Kanya, Fujii, Hiromasa, Georgakilas, Alexandros G., Amedei, Amedeo, Amin, Amr, Helferich, Bill, Boosani, Chandra S., Guha, Gunjan, Ciriolo, Maria Rosa, Chen, Sophie, Mohammed, Sulma I., Azmi, Asfar S., Bhakta, Dipita, Halicka, Dorota, Niccolai, Elena, Aquilano, Katia, Ashraf, S. Salman, Nowsheen, Somaira, Yang, Xujuan
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2015
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600408/
https://ncbi.nlm.nih.gov/pubmed/25869441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2015.03.007
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