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Immunoregulatory Effects of Everolimus on In Vitro Alloimmune Responses

Everolimus (EVL) is a novel mTOR-inhibitor similar to sirolimus (SRL) that is used in organ transplant recipients, often in combination with tacrolimus (TAC) or mycophenolate (MPA). The current study aims to determine its effects on regulatory T cells. Increasing concentrations of EVL, MPA and TAC a...

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Опубликовано в: :PLoS One
Главные авторы: Levitsky, Josh, Miller, Joshua, Huang, Xuemei, Gallon, Lorenzo, Leventhal, Joseph R., Mathew, James M.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898829/
https://ncbi.nlm.nih.gov/pubmed/27275747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156535
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