Načítá se...

Combinatorial protein engineering of proteolytically resistant mesotrypsin inhibitors as candidates for cancer therapy

Engineered protein therapeutics offer advantages, including strong target affinity, selectivity, and low toxicity, but like natural proteins can be susceptible to proteolytic degradation, thereby limiting their effectiveness. A compelling therapeutic target is mesotrypsin, a protease upregulated wit...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Biochem J
Hlavní autoři: Cohen, Itay, Kayode, Olumide, Hockla, Alexandra, Sankaran, Banumathi, Radisky, Derek, Radisky, Evette, Papo, Niv
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898653/
https://ncbi.nlm.nih.gov/pubmed/26957636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20151410
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!