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Pyruvate fuels mitochondrial respiration and proliferation of breast cancer cells: effect of monocarboxylate transporter inhibition

Recent studies have highlighted the fact that cancer cells have an altered metabolic phenotype, and this metabolic reprogramming is required to drive biosynthesis pathways necessary for rapid replication and proliferation. Specifically, the importance of tricarboxylic acid (TCA) cycle-generated inte...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Biochem J
Päätekijät: Diers, Anne R., Broniowska, Katarzyna A., Chang, Ching-Fang, Hogg, Neil
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898201/
https://ncbi.nlm.nih.gov/pubmed/22458763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20120294
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