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Mutation of wrb, a Component of the Guided Entry of Tail-Anchored Protein Pathway, Disrupts Photoreceptor Synapse Structure and Function

PURPOSE: Tail-anchored (TA) proteins contain a single hydrophobic domain at the C-terminus and are posttranslationally inserted into the ER membrane via the GET (guided entry of tail-anchored proteins) pathway. The role of the GET pathway in photoreceptors is unexplored. The goal of this study was t...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Invest Ophthalmol Vis Sci
Egile Nagusiak: Daniele, Lauren L., Emran, Farida, Lobo, Glenn P., Gaivin, Robert J., Perkins, Brian D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Association for Research in Vision and Ophthalmology 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898200/
https://ncbi.nlm.nih.gov/pubmed/27273592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-18996
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