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Post-hoc analysis showing better clinical response with the loading dose of certolizumab pegol in Japanese patients with active rheumatoid arthritis

Objectives: To compare the efficacy and safety of certolizumab pegol (CZP) with and without loading dose (LD) in a post-hoc analysis of two Japanese clinical studies. Methods: Data from the double-blind trials (DBT) J-RAPID and HIKARI, and their open-label extension (OLE) studies, were used. Patient...

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Bibliographische Detailangaben
Veröffentlicht in:Mod Rheumatol
Hauptverfasser: Takeuchi, Tsutomu, Yamamoto, Kazuhiko, Yamanaka, Hisashi, Ishiguro, Naoki, Tanaka, Yoshiya, Eguchi, Katsumi, Watanabe, Akira, Origasa, Hideki, Kobayashi, Mariko, Shoji, Toshiharu, Togo, Osamu, Miyasaka, Nobuyuki, Koike, Takao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898155/
https://ncbi.nlm.nih.gov/pubmed/26472043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/14397595.2015.1109182
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