Amyloid Precursor-Like Protein 2 deletion-induced retinal synaptopathy related to congenital stationary night blindness: structural, functional and molecular characteristics

BACKGROUND: Amyloid precursor protein knockout mice (APP-KO) have impaired differentiation of amacrine and horizontal cells. APP is part of a gene family and its paralogue amyloid precursor-like protein 2 (APLP2) has both shared as well as distinct expression patterns to APP, including in the retina...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Dinet, Virginie, Ciccotosto, Giuseppe D., Delaunay, Kimberley, Borras, Céline, Ranchon-Cole, Isabelle, Kostic, Corinne, Savoldelli, Michèle, El Sanharawi, Mohamed, Jonet, Laurent, Pirou, Caroline, An, Na, Abitbol, Marc, Arsenijevic, Yvan, Behar-Cohen, Francine, Cappai, Roberto, Mascarelli, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4897877/
https://ncbi.nlm.nih.gov/pubmed/27267879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0245-z
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