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Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress
The nucleolus is a potent disease biomarker and a target in cancer therapy. Ribosome biogenesis is initiated in the nucleolus where most ribosomal (r-) proteins assemble onto precursor rRNAs. Here we systematically investigate how depletion of each of the 80 human r-proteins affects nucleolar struct...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4897761/ https://ncbi.nlm.nih.gov/pubmed/27265389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11390 |
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