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DNA Demethylation Rescues the Impaired Osteogenic Differentiation Ability of Human Periodontal Ligament Stem Cells in High Glucose

Diabetes mellitus, characterized by abnormally high blood glucose levels, gives rise to impaired bone remodeling. In response to high glucose (HG), the attenuated osteogenic differentiation capacity of human periodontal ligament stem cells (hPDLSCs) is associated with the loss of alveolar bone. Rece...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Liu, Zhi, Chen, Tian, Sun, Wenhua, Yuan, Zongyi, Yu, Mei, Chen, Guoqing, Guo, Weihua, Xiao, Jingang, Tian, Weidong
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4897703/
https://ncbi.nlm.nih.gov/pubmed/27273319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27447
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