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DNA Demethylation Rescues the Impaired Osteogenic Differentiation Ability of Human Periodontal Ligament Stem Cells in High Glucose

Diabetes mellitus, characterized by abnormally high blood glucose levels, gives rise to impaired bone remodeling. In response to high glucose (HG), the attenuated osteogenic differentiation capacity of human periodontal ligament stem cells (hPDLSCs) is associated with the loss of alveolar bone. Rece...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Zhi, Chen, Tian, Sun, Wenhua, Yuan, Zongyi, Yu, Mei, Chen, Guoqing, Guo, Weihua, Xiao, Jingang, Tian, Weidong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4897703/
https://ncbi.nlm.nih.gov/pubmed/27273319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27447
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