Association-heterogeneity mapping identifies an Asian-specific association of the GTF2I locus with rheumatoid arthritis

Considerable sharing of disease alleles among populations is well-characterized in autoimmune disorders (e.g., rheumatoid arthritis), but there are some exceptional loci showing heterogenic association among populations. Here we investigated genetic variants with distinct effects on the development...

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Udgivet i:Sci Rep
Main Authors: Kim, Kwangwoo, Bang, So-Young, Ikari, Katsunori, Yoo, Dae Hyun, Cho, Soo-Kyung, Choi, Chan-Bum, Sung, Yoon-Kyoung, Kim, Tae-Hwan, Jun, Jae-Bum, Kang, Young Mo, Suh, Chang-Hee, Shim, Seung-Cheol, Lee, Shin-Seok, Lee, Jisoo, Chung, Won Tae, Kim, Seong-Kyu, Choe, Jung-Yoon, Momohara, Shigeki, Taniguchi, Atsuo, Yamanaka, Hisashi, Nath, Swapan K., Lee, Hye-Soon, Bae, Sang-Cheol
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4897688/
https://ncbi.nlm.nih.gov/pubmed/27272985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27563
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