PADI4 and HLA-DRB1 Are Genetic Risks for Radiographic Progression in RA Patients, Independent of ACPA Status: Results from the IORRA Cohort Study

INTRODUCTION: Rheumatoid arthritis (RA) is a systemic, chronic inflammatory disease influenced by both genetic and environmental factors, leading to joint destruction and functional impairment. Recently, a large-scaled GWAS meta-analysis using more than 37,000 Japanese samples were conducted and 13...

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Hlavní autoři: Suzuki, Taku, Ikari, Katsunori, Yano, Koichiro, Inoue, Eisuke, Toyama, Yoshiaki, Taniguchi, Atsuo, Yamanaka, Hisashi, Momohara, Shigeki
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620057/
https://ncbi.nlm.nih.gov/pubmed/23577190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061045
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