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Antithrombin controls tumor migration, invasion and angiogenesis by inhibition of enteropeptidase

Antithrombin is a key inhibitor of the coagulation cascade, but it may also function as an anti-inflammatory, anti-angiogenic, anti-viral and anti-apoptotic protein. Here, we report a novel function of antithrombin as a modulator of tumor cell migration and invasion. Antithrombin inhibited enteropep...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Luengo-Gil, Ginés, Calvo, María Inmaculada, Martín-Villar, Ester, Águila, Sonia, Bohdan, Nataliya, Antón, Ana I., Espín, Salvador, Ayala de la Peña, Francisco, Vicente, Vicente, Corral, Javier, Quintanilla, Miguel, Martínez-Martínez, Irene
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4897635/
https://ncbi.nlm.nih.gov/pubmed/27270881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27544
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