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CRF receptor 1 antagonism and brain distribution of active components contribute to the ameliorative effect of rikkunshito on stress-induced anorexia
Rikkunshito (RKT), a Kampo medicine, has been reported to show an ameliorative effect on sustained hypophagia after novelty stress exposure in aged mice through serotonin 2C receptor (5-HT(2C)R) antagonism. We aimed to determine (1) whether the activation of anorexigenic neurons, corticotropin-relea...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4897628/ https://ncbi.nlm.nih.gov/pubmed/27273195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27516 |
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