MYC — a thorn in the side of cancer immunity

For decades, MYC has been known for its role in regulating cancer cell proliferation and survival. In a recent paper published in Science, Casey et al. have uncovered a new function for MYC in promoting immune evasion by directly regulating expression of programmed death-ligand 1 (PD-L1) and CD47 on...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Res
Prif Awduron: Spranger, Stefani, Gajewski, Thomas F, Kline, Justin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Research Highlight
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4897180/
https://ncbi.nlm.nih.gov/pubmed/27113275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.50
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