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Impact of oncogenic pathways on evasion of antitumour immune responses

Immunotherapeutic interventions are showing effectiveness across a wide range of cancer types, but only a subset of patients shows clinical response to therapy. Responsiveness to checkpoint blockade immunotherapy is favoured by the presence of a local, CD8(+) T cell-based immune response within the...

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Pubblicato in:Nat Rev Cancer
Autori principali: Spranger, Stefani, Gajewski, Thomas F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685071/
https://ncbi.nlm.nih.gov/pubmed/29326431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc.2017.117
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