Loss of MeCP2 in cholinergic neurons causes part of RTT-like phenotypes via α7 receptor in hippocampus

Mutations in the X-linked MECP2 gene cause Rett syndrome (RTT), an autism spectrum disorder characterized by impaired social interactions, motor abnormalities, cognitive defects and a high risk of epilepsy. Here, we showed that conditional deletion of Mecp2 in cholinergic neurons caused part of RTT-...

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Publicat a:Cell Res
Autors principals: Zhang, Ying, Cao, Shu-Xia, Sun, Peng, He, Hai-Yang, Yang, Ci-Hang, Chen, Xiao-Juan, Shen, Chen-Jie, Wang, Xiao-Dong, Chen, Zhong, Berg, Darwin K, Duan, Shumin, Li, Xiao-Ming
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4897179/
https://ncbi.nlm.nih.gov/pubmed/27103432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.48
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