Sulforaphane reduces lipopolysaccharide-induced proinflammatory markers in hippocampus and liver but does not improve sickness behavior

OBJECTIVES: Acute peripheral infection is associated with central and peripheral inflammation, increased oxidative stress, and adaptive sickness behaviors. Sulforaphane (SFN) activates the transcription factor nuclear factor E2-related factor 2 (Nrf2), which upregulates antioxidant genes and lowers...

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Bibliographic Details
Published in:Nutr Neurosci
Main Authors: Townsend, Brigitte E., Johnson, Rodney W.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896864/
https://ncbi.nlm.nih.gov/pubmed/26639573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/1028415X.2015.1103463
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