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Sulforaphane induces Nrf2 target genes and attenuates inflammatory gene expression in microglia from brain of young adult and aged mice

Increased neuroinflammation and oxidative stress resulting from heightened microglial activation is associated with age-related cognitive impairment. The objectives of this study were to examine the effects of the bioactive sulforaphane (SFN) on the nuclear factor E2-related factor 2 (Nrf2) pathway...

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Detalhes bibliográficos
Publicado no:Exp Gerontol
Main Authors: Townsend, Brigitte E., Johnson, Rodney W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713291/
https://ncbi.nlm.nih.gov/pubmed/26571201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2015.11.004
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