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A TGF-β pathway associated with cancer cachexia

Cancer cachexia leads to involuntary weight loss resulting from the atrophy of skeletal muscle and adipose tissues. Now, in metastatic mouse models of cancer, investigators reveal a cross talk pathway between bone and muscle that provides a new understanding of wasting in advanced cancers.

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Détails bibliographiques
Publié dans:Nat Med
Auteur principal: Guttridge, Denis C
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896299/
https://ncbi.nlm.nih.gov/pubmed/26540384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3988
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